Based on popular 1980 video game, Rampage (2018) tracks the effects of genetic modification of animals that turn into extremely aggressive monsters. Primatologist Davis Okoye, a man who holds people at a distance, shares a close connection with George, an extraordinarily intelligent gorilla who has been in his care since birth. But when a reprobable genetic experiment fails, this mild monkey turns into a frightening monster. Soon, things get worse as other alpha predators whose DNA is altered are discovered. While these newborn monsters invade North America, destroying everything in their path, Okoye joins with a discredged genetic engineer to find an antidote, struggling to reach his goal in an ever-changing battlefield, Not only to stop a global catastrophe, but also to save George, the creature that once was his friend.