Dr. Anna Fox (Amy Adams) is a child psychologist who, after a traumatic experience, suffers from severe agoraphobia. This panic to open spaces makes her live alone, without leaving her home in New York. There, he takes photos of his neighbors, and spies on their lives. Until one day she hears a chilling scream from the Russell house, a family that everyone admires and considers exemplary. After witnessing this disturbing act of violence, Anna will be confused and scared, and will begin to wonder if this attack really took place.