Humanity is about to disappear forever. A virus has transformed the population into destructive creatures. The WICKED organization is looking for a cure and doing a series of tests on young people. Some of these survivors are trying to help others escape in a safe place. This is the case of Thomas and his friends who joined a group of resistance. Their goal is to reach the Last City where they can find answers to all their questions. His enemies want him all the time to find him at any price, dead or alive.