The film tells the story of a feminine drug master, Griselda Blanco, a pioneer in cocaine trafficking. At just 17, Griselda managed to get to the US with a false passport with her first husband, Carlos. He lived for a while in Queens with his three sons and continued his illegal business, being attracted by rapid gains. In drug trafficking, Griselda has always used beautiful women but also children as carriages and has created false-assault boots to be able to carry their drugs. His children abandoned school and joined their mother’s business.