After exhausting all the savings he had so far enlisted to enroll a basketball team in a Harlem tournament, Dax has a lot of obstacles he does not expect and over which he is very hard to pass – one of them was the loss of the team in favor of a great rival. Being desperate to win the tournament and get his hands on the big prize money, Dax meets the unique, legendary Uncle Drew and convinces him to return to the field for a last big match and help him win this tournament. The two then go on a trip together to recruit their former teammates and show that a group of seventeen still have what they need to make a show.